The Biomedical Resource Ontology (BRO) to enable resource discovery in clinical and translational research.

TitleThe Biomedical Resource Ontology (BRO) to enable resource discovery in clinical and translational research.
Publication TypeJournal Article
Year of Publication2011
AuthorsTenenbaum, Jessica D., Whetzel Patricia L., Anderson Kent, Borromeo Charles D., Dinov Ivo D., Gabriel Davera, Kirschner Beth, Mirel Barbara, Morris Tim, Noy Natasha, Nyulas Csongor, Rubenson David, Saxman Paul R., Singh Harpreet, Whelan Nancy, Wright Zach, Athey Brian D., Becich Michael J., Ginsburg Geoffrey S., Musen Mark A., Smith Kevin A., Tarantal Alice F., Rubin Daniel L., and Lyster Peter
JournalJ Biomed Inform
Volume44
Issue1
Pagination137-45
Date Published2011 Feb
ISSN1532-0480
KeywordsAnimals, Biomedical Research, Computational Biology, Database Management Systems, Documentation, Humans, Internet, Medical Informatics, Semantics, Translational Medical Research, User-Computer Interface
Abstract

The biomedical research community relies on a diverse set of resources, both within their own institutions and at other research centers. In addition, an increasing number of shared electronic resources have been developed. Without effective means to locate and query these resources, it is challenging, if not impossible, for investigators to be aware of the myriad resources available, or to effectively perform resource discovery when the need arises. In this paper, we describe the development and use of the Biomedical Resource Ontology (BRO) to enable semantic annotation and discovery of biomedical resources. We also describe the Resource Discovery System (RDS) which is a federated, inter-institutional pilot project that uses the BRO to facilitate resource discovery on the Internet. Through the RDS framework and its associated Biositemaps infrastructure, the BRO facilitates semantic search and discovery of biomedical resources, breaking down barriers and streamlining scientific research that will improve human health.

DOI10.1016/j.jbi.2010.10.003
Alternate JournalJ Biomed Inform
PubMed ID20955817
PubMed Central IDPMC3050430
Grant List1UL1RR024128-01 / RR / NCRR NIH HHS / United States
1UL1RR024153-01 / RR / NCRR NIH HHS / United States
1UL1RR024986-01 / RR / NCRR NIH HHS / United States
1UL1RR025008-01 / RR / NCRR NIH HHS / United States
3U54DA021519-04S1 / DA / NIDA NIH HHS / United States
3U54HG004028-04S1 / HG / NHGRI NIH HHS / United States
3UL1RR024153-03S1 / RR / NCRR NIH HHS / United States
5U54HG004028-05 / HG / NHGRI NIH HHS / United States
5UL1RR024128-03S1 / RR / NCRR NIH HHS / United States
U54 RR021813 / RR / NCRR NIH HHS / United States
U54DA021519 / DA / NIDA NIH HHS / United States
UL1 RR024128 / RR / NCRR NIH HHS / United States
UL1 RR024128-01 / RR / NCRR NIH HHS / United States
UL1 RR024128-03S1 / RR / NCRR NIH HHS / United States
UL1 TR000454 / TR / NCATS NIH HHS / United States
UL1RR024146 / RR / NCRR NIH HHS / United States