The University of Michigan Honest Broker: a Web-based service for clinical and translational research and practice.

TitleThe University of Michigan Honest Broker: a Web-based service for clinical and translational research and practice.
Publication TypeJournal Article
Year of Publication2009
AuthorsBoyd, Andrew D., Saxman Paul R., Hunscher Dale A., Smith Kevin A., Morris Timothy D., Kaston Michelle, Bayoff Frederick, Rogers Bruce, Hayes Pamela, Rajeev Namrata, Kline-Rogers Eva, Eagle Kim, Clauw Daniel, Greden John F., Green Lee A., and Athey Brian D.
JournalJ Am Med Inform Assoc
Volume16
Issue6
Pagination784-91
Date Published2009 Nov-Dec
ISSN1527-974X
KeywordsBiomedical Research, Computer Security, Humans, Information Dissemination, Information Systems, Interdisciplinary Communication, Interinstitutional Relations, Internet, Michigan, User-Computer Interface
Abstract

For the success of clinical and translational science, a seamless interoperation is required between clinical and research information technology. Addressing this need, the Michigan Clinical Research Collaboratory (MCRC) was created. The MCRC employed a standards-driven Web Services architecture to create the U-M Honest Broker, which enabled sharing of clinical and research data among medical disciplines and separate institutions. Design objectives were to facilitate sharing of data, maintain a master patient index (MPI), deidentification of data, and routing data to preauthorized destination systems for use in clinical care, research, or both. This article describes the architecture and design of the U-M HB system and the successful demonstration project. Seventy percent of eligible patients were recruited for a prospective study examining the correlation between interventional cardiac catheterizations and depression. The U-M Honest Broker delivered on the promise of using structured clinical knowledge shared among providers to help clinical and translational research.

DOI10.1197/jamia.M2985
Alternate JournalJ Am Med Inform Assoc
PubMed ID19717803
PubMed Central IDPMC3002130
Grant ListHHSN268200425212C / / PHS HHS / United States
U54-DA021519 / DA / NIDA NIH HHS / United States
UL1RR024986 / RR / NCRR NIH HHS / United States